The study attempted to investigate the attitude of parents and family members towards their mentally retarded children. The study also aimed to find out the levels of differences among the attitude of parents and family members and to know the impact of gender on the attitude of the same. The sample consisted of 50 parents and 50 family members of institutionalized mentally retarded children. Two attitude scales were constructed, one each for parents and family members, on the basis of likert‟s 5 point scale. Data were analyzed using descriptive statistics and t-test. The results indicated that the parents and family members have positive attitude towards mentally retarded children. However, their attitude towards mentally retarded children was affected by their individual knowledge, beliefs and perceptions. Further there was no any gender impact on the attitude of parents towards the retarded children. But the impact of gender was found significant on the attitude of family members.