Human movement is governed by a complex interaction of biomechanical, physiological, and neuromuscular factors that collectively determine movement efficiency, stability, and functional performance. Understanding these biomechanical factors is essential for improving athletic performance, preventing musculoskeletal injuries, enhancing rehabilitation outcomes, and promoting overall physical health. This study investigates the influence of biomechanical factors on human movement patterns, with particular emphasis on joint mobility, muscle strength, balance, posture, and neuromuscular coordination. A quantitative cross-sectional research design was employed, and primary data were collected from 250 participants using a structured questionnaire based on a five-point Likert scale. Descriptive statistics, mean score analysis, percentage analysis, and regression analysis were applied to evaluate the relationships among biomechanical variables and movement performance. The findings indicate that muscle strength and joint mobility are the strongest determinants of efficient human movement, while balance, posture, and neuromuscular coordination significantly contribute to functional stability and movement accuracy. Furthermore, strength training, flexibility exercises, and balance training emerged as effective strategies for improving movement efficiency and reducing injury risk. The study emphasizes the importance of integrating biomechanical assessment into sports science, rehabilitation, physiotherapy, and clinical practice to optimize movement quality. The findings provide evidence-based recommendations for healthcare professionals, physiotherapists, sports scientists, and fitness practitioners in designing effective movement enhancement and injury prevention programs.