ERYTHROPOIETIN ABUSE IN SPORT: A HEALTH HAZARD APPROACH
Keywords:
Erythropoietin, Sport and Side effectAbstract
In endurance domain sports disciplines the role the supply of oxygen to muscles plays a significant role. Indeed, muscle performance declines during prolonged and intense activity as a consequence of the shift from the aerobic to the anaerobic metabolism with an increase of lactate. To enhance the aerobic capacity two alternatives may be used: increasing either the transport or the delivery of oxygen. In this setting, erythropoietin use is the practice of illicitly using a drug to improve athletic performances. In the present overview, old and newer erythropoietic stimulating molecules are described with a special emphasis on their potential side effects. Direct and indirect detection methods are briefly described with the aim of mentioning their roles and limits with regard to anti-doping strategies. The purpose of this review is to consider EPO abuse in sport, health hazards and risks of use of EPO by athletes. Analytical
methods was used for this paper by reviewing relevant publications, primarily based on the online sports medicine journals available on Internet, Wikipedia, Elsevier, PubMed and National Anti Doping Agency literature.
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References
Ashenden M, Varlet-Marie E, Lasne F and Audran M. (2006) The effects of microdose recombinant human erythropoietin regimens in athletes. Haematological.2006;91(8): 1143–1144.
B.M.J Book, (2002) Drugs in Sport: The pressure to perform, BMA House, Tavistock Square, London, WC1H 9JR, ISBN 0 7279 1606 8.
Brien, A.J, Simon, T.L: (1987) The effects of red blood cell infusion on 10-km race time. JAMA 1987; 257: 2761-2765.
Brown, W. M. (1980). Ethics, Drugs and Sport. Journal of the Philosophy of Sport VII:15-23.
Coyle EF, Coggan AR, Hopper MK, Walters TJ.(1988) Determinants of endurance in well-trained cyclists. Journal of Applied Physiology. 1988; 64: 2622-2630.
Enoksen E, Shalfawi SA, Tonnessen E. (2011) The effect of high- vs. low-intensity training on aerobic capacity in well-trained male middle-distance runners. Journal of Strength Conditioning. Res 2011; 25: 812-818.
Gore C,J Parisotto, et al. (2003) Second-generation blood tests to detect erythropoietin abuse by athletes. Hematological 2003; 88: 333-344.
Heuberger J, et al (2012) Erythropoietin doping in cycling: Lack of evidence for efficacy and a negative risk-benefit. British Journal of Clinical Pharmacology. 2012; DOI: 10.1111/bcp.12034
Ivan Waddington and Andy Smith (2009) An Introduction to Drugs in Sport, Routledge 270, Madison Avenue, New York 10016.
Mandeep Singh Nathial, Analysis of set shot in basketball in relation with time to perform the course and displacement of center of gravity, American Journal of Sports Science, Vol.2 Issue.5 pp: 122-126 (2014). Retrieved from https://www.sciencepublishinggroup.com/journal/paperinfo.aspx?journalid=155& doi=10.11648/j.ajss.20140205.13
Mandeep Singh (2010). Evaluation And Improvement of Sports Techniques Through Biomechanical Updated Analyzing Technology, University News, Journal of Higher Education Association of Indian Universities, Association of Indian Universities, Vol:48:Issue.05;2010 Pp45-57, 2010
Mandeep Singh Nathial, A Study of Adjustment and Emotional Intelligence of University Coaches in India, American Journal of Applied Psychology. Volume 3, Issue 6, November 2014, pp. 122-126. doi: 10.11648/j.ajap.20140306.11
Nathial, mandeep singh. A COMPARATIVE AND ANALYTICAL STUDY OF SELF-ESTEEM AND JOB SATISFACTION IN ATHLETES AND NON ATHLETES. Journal of Advances in Social Science and Humanities, 2(10). https://doi.org/10.15520/jassh210123
Singh, M., Kour, R., & Kour, A., A collaborative diversified investigation of respective responses of sports person coaches and organizations on criminalization of doping. International Journal of Health Sciences, 6 (S3), 11295–11310. https://doi.org/10.53730/ijhs.v6nS3.8641
Mandeep Singh., Assessment of Vocational Interests of Pahadi & Bakarwal School Students In Relation To Their Gender. Int J Recent Sci Res. 9(3), pp. 24817-24819.
DOI: http://dx.doi.org/10.24327/ijrsr.2018.0903.1731
Singh, M., & Deol, N. S.; KINEMATICAL ANALYSIS OF HIGH DRIVE IN SOCCER. INTERNATIONAL JOURNAL OF RESEARCH PEDAGOGY AND TECHNOLOGY IN EDUCATION AND MOVEMENT SCIENCES, 1(01). Retrieved from https://ijems.net/index.php/ijem/article/view/5
